Coronavirus disease (COVID-19): How is it transmitted? Jamilloux Y, Henry T, Belot A, Viel S, Fauter M, El Jammal T, Walzer T, Franois B, Sve P. Should we stimulate or suppress immune responses in COVID-19? However, antibody kinetics of different immunoglobulins have not been well characterized, and reported findings are conflicting (12). Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis. Gebhard C, Regitz-Zagrosek V, Neuhauser HK, Morgan R, Klein SL. Although the clinical and laboratory characteristics of COVID-19 patients have been well characterized, the pathophysiological mechanisms underlying disease severity and progression remain unclear. Gould TJ, Vu TT, Swystun LL, Dwivedi DJ, Mai SHC, Weitz JI, Liaw PC. No conflicts of interest, financial or otherwise, are declared by the author(s). Zuo Y, Yalavarthi S, Shi H, Gockman K, Zuo M, Madison JA, Blair C, Weber A, Barnes BJ, Egeblad M, Woods RJ, Kanthi Y, Knight JS. Interestingly, SARS-CoV-2 has developed a unique S1/S2 cleavage site in its S protein, characterized by a four-amino acid insertion, which seems to be absent in all other coronaviruses (4). This is in contrast to what has been observed in other respiratory viruses, including SARS-CoV (142). The pyrin inflammasome in health and disease. Spike protein mRNA are injected into the body. Most studies have reported no evidence of detectable SARS-CoV-2 RNA in the placenta. Chiotos K, Bassiri H, Behrens EM, Blatz AM, Chang J, Diorio C, Fitzgerald JC, Topjian A, John ARO. Liver biochemistries in hospitalized patients with COVID-19. The immune system now has the tools to defeat the SARS-CoV-2 virus. Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, Barnaby DP, Becker LB, Chelico JD, Cohen SL, Cookingham J, Coppa K, Diefenbach MA, Dominello AJ, Duer-Hefele J, Falzon L, Gitlin J, Hajizadeh N, Harvin TG, Hirschwerk DA, Kim EJ, Kozel ZM, Marrast LM, Mogavero JN, Osorio GA, Qiu M, Zanos TP; the Northwell COVID-19 Research Consortium . Researchers Discover Mechanisms Behind Emergence of COVID